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桥本消瘿方治疗桥本氏甲状腺炎的临床研究.docx

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桥本消瘿方治疗桥本氏甲状腺炎的临床研究 Title:ClinicalStudyontheTreatmentofHashimoto'sThyroiditiswithQiaobenXiaoyingFang Abstract: Hashimoto'sthyroiditisisachronicautoimmunediseasecharacterizedbyinflammationofthethyroidgland.TraditionalChineseMedicine(TCM)providesaholisticapproachtotreatingthiscondition,withQiaobenXiaoyingFangbeingacommonlyprescribedherbalformula.ThisstudyaimstoevaluatetheclinicalefficacyandsafetyofQiaobenXiaoyingFanginthetreatmentofHashimoto'sthyroiditis.Acomprehensiveliteraturereview,includingrandomizedcontrolledtrials(RCTs)andclinicalstudies,wasconductedtoanalyzetheavailableevidence.ThefindingsofthisstudyhighlightthepotentialofQiaobenXiaoyingFangasaneffectiveandsafetreatmentforHashimoto'sthyroiditis,thusprovidingvaluableinsightsforclinicalpractice. Introduction: Hashimoto'sthyroiditis,alsoknownaschroniclymphocyticthyroiditis,isthemostcommonautoimmunethyroiddisorder.Itischaracterizedbytheinfiltrationoflymphocytesandthedestructionofthyroidfollicularcells,leadingtothyroiddysfunction.TheconventionaltreatmentforHashimoto'sthyroiditisprimarilyinvolvesthyroidhormonereplacementtherapy.However,itisessentialtoexplorealternativeremediesthatmayprovideadditionaltherapeuticbenefitsandimprovepatients'qualityoflife. TCM,withitsholisticandindividualizedapproach,hasbeenwidelyusedinthetreatmentofvariousendocrinedisorders,includingHashimoto'sthyroiditis.QiaobenXiaoyingFang,aTCMherbalformula,hasbeenreportedtohavesignificanttherapeuticeffectsonthyroidfunctionandautoimmuneresponse.ThisstudyaimstosystematicallyreviewandanalyzetheavailableevidencetoevaluatetheeffectivenessandsafetyofQiaobenXiaoyingFanginthetreatmentofHashimoto'sthyroiditis. Methods: Acomprehensivesearchofmultipleelectronicdatabases,includingPubMed,WebofScience,andCochraneLibrary,wasconductedtoidentifyrelevantstudies.Onlyrandomizedcontrolledtrials(RCTs)andclinicalstudiesevaluatingtheeffectsofQiaobenXiaoyingFangonHashimoto'sthyroiditiswereincluded.Thedataextractionandqualityassessmentwereperformedindependentlybytworeviewers,a