超声造影鉴别诊断甲状腺结节良恶性的价值.pdf

中国医学影像技术2010年第26卷第8期ChinJMedImagingTechnol,2010,Vol26,No8∀1441∀

头颈部影像学

Valueofcontrastenhancedultrasonographyindifferentialdiagnosisof
benignormalignantthyroidnodules

ZHAOYing,HUANGDaozhong*,HUANGXiaoli
(DepartmentofMedicalUltrasound,TongjiHospitalofTongjiMedicalCollegeofHuazhong
UniversityofScience&Technology,Wuhan430030,China)

[Abstract]ObjectiveToinvestigatethevalueofcontrastenhancedultrasonography(CEUS)inthedifferentialdiagnosis
ofbenignormalignantthyroidnodules.MethodsColorDopplerflowimaging(CDFI)andcontrastenhancedultrasonogra
phyperfusionof39thyroidnoduleswereretrospectivelyanalyzed.Thefillingintensityofbothperipheryandinteriorofthe
nodulebythetimeintensitycurve(TIC)wasobserved.Theevaluatedparametersincludedpeakintensity(PI)oftheperiph
ery,interiorintensity(II)atthePItime,thedifferenceofPIandI(I).Thenthediagnosticcutofpointsforthyroidbe
nignormalignantthyroidnoduleswascalculated.ResultsMostofthemalignantthyroidnoduleswerefilledSonoVueperva
sively(9412%).Mostofthebenignthyroidnodulesshowedearlywashinoftheperiphery(8636%),andthemajority
showedringenhancementatperiphery,slightornoneenhancementininterior.ItwaspronetobenignnodulewhenI>
608dB,andthesensitivitywas8571%.Simultaneously,itwaspronetomalignantnodulewhenI<289dBandthe
sensitivitywas8235%.ConclusionCEUSisvaluableinthedifferentialdiagnosisofbenignormalignantthyroidnodules.
[Keywords]Thyroidnodule;Ultrasonography;Contrastmedia;Timeintensitycurve

超声造影鉴别诊断甲状腺结节良恶性的价值

赵莹,黄道中*,黄小莉
(华中科技大学同济医学院附属同济医院超声影像科,湖北武汉430030)

[摘要]目的探讨超声造影对鉴别诊断甲状腺结节良恶性的价值。方法回顾性分析39个甲状腺结节的彩色多普
勒血流显像及超声造影灌注过程,观察病灶周边及内部造影剂灌注强度,通过时间强度曲线分析,比较病灶周边感兴趣区
(ROI)峰值强度(PI)与达峰时刻病灶内部ROI相对应的造影剂灌注强度(II)的差异程度,计算两者差值I及诊断良、恶性
结节的I分界值。结果甲状腺恶性结节造影增强模式多为弥漫性整体增强(9412%),良性结节多为周边先于内部增
强(8636%),并以周边环状增强为主,内部轻微增强或始终无增强。初步界定I>608dB时,良性结节可能性大,敏感
度为8571%;I<289dB时,恶性结节可能性大,敏感度为8235%。结论超声造影对鉴别甲状腺结节的良恶性有一
定实用价值。
[关键词]甲状腺结节;超声检查;造影剂;时间强度曲线
[中图分类号]R7361;R4451[文献标识码]A[文章编号]10033289(2010)08144103

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