预览加载中,请您耐心等待几秒...
1/6
2/6
3/6
4/6
5/6
6/6

在线预览结束,喜欢就下载吧,查找使用更方便

如果您无法下载资料,请参考说明:

1、部分资料下载需要金币,请确保您的账户上有足够的金币

2、已购买过的文档,再次下载不重复扣费

3、资料包下载后请先用软件解压,在使用对应软件打开

靶控输注右美托咪啶对全身麻醉诱导期的影响 [摘要]目的:探究靶控输注右美托咪啶对胸外科手术患者全身麻醉诱导期的影响。方法:将我院2011年3月至2012年3月期间的108例进行胸外科全麻手术的患者随机分成两组,每组54例,B组采用常规麻醉诱导,A组在常规麻醉诱导的基础上靶控输注右美托咪啶,分别从两组患者的循环变化和应激相关指标变化分析靶控输注右美托咪啶对胸外科手术患者全身麻醉诱导期的影响。结果:A、B组患者的MAP水平在T3、T4时刻(A组T3:79.04±9.54,T4:68.12±12.81;B组T3:73.39±9.03T4:63.94±14.71)较T1时刻(A组T1:86.72±13.46;B组T1:85.67±9.93),A组(T3:t=7.954,T4:t=10.038),B组T3:t=9.375,T4:t=13.903),p均<0.05,两组间比较,B组患者的MAP水平较A组MAP水平均显著降低,t=5.173,P<0.05,具有统计学意义;A、B组患者的Cor水平均比T1时显著降低;两组患者的血糖水平在T4时刻较T1显著降低,A组(T4:t=4.857,P<0.05),B组(T4:t=4.038,P<0.05),P均<0.05,具有统计学意义。两组患者的各个时刻的HR、SPO2、Lac水平变化等均无显著性差异,P均>0.05,不具有统计学意义。结论:靶控输注右美托咪啶能明显减少胸外科手术患者全身麻醉诱导期患者的血流动力学紊乱和应激反应,值得在临床中应用。 [关键词]右美托咪啶;胸外科;全身麻醉;影响 ReactionbyTarget-controlledInfusinofDexmedetomidineinThoracicSurgeryPatientsduringInductionofGeneralAnesthesia [Abstract]Objective:Toexploretheinfluenceoftargeted-controlledinfusionofdexmedetomidineinpatientsundergoingthoracicsurgeryduringgeneralanesthesiainductionperiod.Methods:108patientsreceivedthoracicsurgeryinourhospitalfromMarch2011toMarch2012weredividedintotwogroupsrandomly.GroupB(54cases)wereintervencedbynormalmethods.GroupA(54cases)wereintervenedbytarget-controlledinfusionofdexmedetomidine.Thecirculationandstresschangewereobservedinthetwogroupstoanalyzetheimpactoftargeted-controlledinfusionofdexmedetomidineinthoracicsurgerypatientsduringinductionofgeneralanesthesia.Results:ComparedwithT1(AT1:86.72±13.46;BT1:85.67±9.93),MAPsignificantlydecreasedinbothgroupsatT2~T4(AT3:79.04±9.54,T4:68.12±12.81;BT3:73.39±9.03T4:63.94±14.71),A(T3:t=7.954,T4:t=10.038),B(T3:t=9.375,T4:t=13.903),P<0.05.MAPingroupBwassignificantlylowerthaningroupA(P<0.05).ComparedwithT1,CoratT4decreasedsignificantlyinbothgroupsA(T4:t=4.857,P<0.05),B(T4:t=4.038,P<0.05),(P<0.05).ComparedwithT1,Gluweredecreasedsignificantlyinbothgroups(P<0.05).ComparedwithT1,thelevelsofHR,andSPO2andLacdonotdecreasedorincreasedsignificantlyinbothgroups.(P>0.05)Conclusion:TheTargeted-contrclledinfusionofdexmedetomidinecandecreasethehemodynamicsandstressreaction