探讨稳心颗粒与胺碘酮联合治疗老年心衰并室性早搏的临床效果.docx

探讨稳心颗粒与胺碘酮联合治疗老年心衰并室性早搏的临床效果【摘要】目的：研究分析稳心颗粒与胺碘酮联合治疗老年心衰并室性早搏的临床效果。方法：此次研究的对象是选择我院2009年10月至2011年10月老年慢性心力衰竭患者80例，将其临床资料进行回顾性分析，并将患者分为两组，观察组和对照组。两组患者均给予卧床休息、吸氧治疗等，根据病情给予强心苷类药物强心治疗、利尿剂利尿、血管扩张药及ACEI类药物，严重短阵室速患者及多源多形室早患者可先给予利多卡因控制后再给予口服药物。对照组患者同时口服胺碘酮0.2g，每天3次，连续应用7天后，改为每次0.2g，每天2次，再连续服用7天后，再改为每次0.2g，每天1次。观察组患者给予胺碘酮0.2g，每天3次，连续服用7天后改为每次0.1g，每天1次。同时服用步长稳心颗粒，每次1袋，每天3次。两组患者均治疗28天。结果：两组患者均未出现影响继续治疗的不良反应。观察组总有效率（95.0%）显著高于对照组总有效率（77.5%），差异有统计学意义（P<0.05）.结论：稳心颗粒与胺碘酮联合治疗老年慢性心力衰竭和并室性早搏过程中，临床效果显著，值得借鉴。【关键词】稳心颗粒；胺碘酮；心力衰竭；室性早搏Objective:TostudytheclinicaleffectofWenxinGranuleCombinedwithamiodaroneinthetreatmentofsenileheartfailureandventricularprematurebeat.Methods:thesubjectsofthisstudyistoselectpatientsinourhospitalfromOctober2009toOctober2011,80casesofelderlypatientswithchronicheartfailure,theclinicaldatawereretrospectivelyanalyzed,andthepatientswerepidedintotwogroups,observationgroupandcontrolgroup.Twogroupsofpatientsweretreatedwithbedrest,oxygeninhalationtherapy,accordingtotheconditionofgivencardiacglycosidestreatment,cardiacdiuretic,vasodilatordrugsandACEI,severeparoxysmalventriculartachycardiapatientsandmultiplepolymorphicventricularcangivepatientsearlyafterorallidocainetocontroldrug.Patientsinthecontrolgroupweretreatedwithamiodarone0.2g,3timesaday,aftercontinuousapplicationfor7days,eachtime0.2g,everydayfor2times,andthentakeitforanother7days,andthenchangedto0.2geverytime,everydayfor1times.Thepatientsintheobservationgroupweregivenamiodarone0.2g3timesadayfor7daysandthenchangedto0.1geverytime,everydayfor1times.Atthesametime,takethepaceofWenxinGranules,1bagseachtime,3timesaday.Twogroupsofpatientsweretreatedfor28days.Results:therewasnoadversereactionintwogroups.Thetotalefficiencyoftheobservationgroup(95%)wassignificantlyhigherthanthecontrolgroupinthetotalefficiency(77.5%),thedifferencewasstatisticallysignificant(P<0.05).Conclusion:WenxinGranulesandamiodaroneinthetreatmentofelderlypatientswithchronicheartfailureandventricularprematurebeatintheprocess,theclinicaleffectissignificant,