不同品种花椒药效比较研究.docx

编号：时间：2021年x月x日书山有路勤为径，学海无涯苦作舟页码：第页共NUMPAGES7页第PAGE\*MERGEFORMAT7页共NUMPAGES\*MERGEFORMAT7页不同品种花椒药效比较研究李惠勇刘友平李旻张玲范婧娴（成都中医药大学，成都，610075）摘要目的：比较花椒和青椒的主要药效作用。方法：采用番泻叶致小鼠急性腹泻实验观察花椒的抗腹泻作用；采用小鼠扭体法实验观察其镇痛作用；采用炭末推进法观察其对正常小鼠小肠运动的影响。结果：对番泻叶致小鼠急性腹泻，花椒、青椒均有显著的抗腹泻作用且花椒较青椒作用强；对醋酸所致疼痛，花椒有显著的镇痛作用，青椒镇痛作用不明显。花椒和青椒均能抑制正常小鼠的小肠推进运动，且花椒作用明显强于青椒。结论：花椒和青椒均有明显的抗腹泻、抑制小鼠小肠推进运动作用且花椒作用较强；花椒有明显的镇痛作用，青椒镇痛作用不明显。关键词花椒；青椒；抗腹泻；镇痛；小肠推进StudyonefficacyofdifferentvarietiesofChinesepricklyashLIHui-yong,LIUYou-ping,LIMing,ZHANGLing,FANJing-xian(ChengduUniversityofTCM,chengdu610075,China)Abstract:Object:Tocomparethemainefficacyofzanthoxylumbungeanummaximandz.schinifoliumsieb.etzucc.Methods:SennaisusedtomicetoacutediarrheaChinesepricklyashexperimentalobservationoftheanti-diarrhea;writhinginmicebyusingexperimentalobservationofitsanalgesiceffectattheendofpromotingtheuseofcarbonobservedinnormalmiceontheimpactofsmallbowelmovement.Results:Sennaonthemousecausedbyacutediarrhoea,zanthoxylumbungeanummaximandz.schinifoliumsieb.etzucchavesignificantroleintheanti-diarrheaandzanthoxylumbungeanummaximstrongerrolethanz.schinifoliumsieb.etzucc;thepaincausedbyaceticacid,thetwohavesignificantanalgesiceffect,z.schinifoliumsieb.etzuccandanalgesiceffectsisnotobvious.Zanthoxylumbungeanummaximandz.schinifoliumsieb.etzucc.innormalmicecouldinhibitthemovementpromotingthesmallintestine,andthefronteffectisstrongerthanthelatter.Conclusion:Zanthoxylumbungeanummaximandz.schinifoliumsieb.etzuccareobviouslyanti-diarrhea,intestinalinhibitedmiceandpepperroleinpromotingthemovementstrongerrole;thefronthasclearanalgesiceffect,thelatteranalgesiceffectwasnotobvious.Keywords:Zanthoxylumbungeanummaxim,z.schinifoliumsieb.etzuccanti-diarrhea;analgesia;HYPERLINK"javascript:sho