子宫内膜癌保留卵巢功能的治疗对患者预后的影响.docx

子宫内膜癌保留卵巢功能的治疗对患者预后的影响[摘要]目的：探讨卵巢移位术辅以放疗和激素替代疗法对子宫内膜癌患者预后的影响。方法：选早期无转移的子宫内膜癌患者105例按告知自愿的原则分A组（全切除组）、B组（卵巢保留组）、C组（卵巢保留+放疗组）、D组（卵巢保留+放疗+激素组）。A组30例采用子宫全切除术治疗；B组25例采用子宫全切除术+卵巢移位术治疗；C组34例采用子宫全切除术+卵巢移位术+放射治疗；D组16例采用子宫全切除术+卵巢移位术+放射+激素替代治疗。比较各组患者术后5年存活率、血清性激素水平及生活质量。结果：5年存活率比较A组和B组无明显差异（P>0.05）C组和D组明显高于A、B组（P[关键词]子宫内膜癌；卵巢移位术；放射治疗；激素替代疗法[中图分类号]R713R737.33[文献标识码]A[文章编号]1673-7210（2007）12（b）-026-03EffectsoftheovaryreservationthearpyonprognosisofpatientswithendometrialcancerWANGLi1ZHANGJia-wen2*(1.PengzhouHealthHospitalforWomenandChildrenofSichuanProvincePengzhou611900China;2.TheDepartmentofGynecologyandObstetricsthe2ndWestChinaHospitalofSichuanUniversityChengdu610000China)[Abstract]Objective:Toexploretheinfluenceofovarytranspositionwithradiotherapyorhormonereplacementtherapyonthepatientswithendometrialcancer.Methods:105patientswithendometrialcancerweredividedinto4groups.30casesasgroupA(totalresection)underwentuterustotalresection25casesasgroupB(ovaryreservation)underwentuterustotalresectionandtranspositionofovary34casesasgroupC(ovaryreservation+radiotherapy)underwentradiotherapyafterthetranspositionofovaryand16casesasgroupD(ovaryreservation+radiotherapy+HRT)weretreatedwithhormonereplacementtherapy(HRT)afterradiotherapyandovarytransposition.Thefive-yearsurvivalratesexhormonelevelandclinicalsituationwerecompared.Results:Thefive-yearsurvivalratehadnodifferencebetweengroupAandBwhiletheywerehigheringroupCandDthangroupA.ThebalancesofserumsexhormoneingroupBCandDwerebetterthanthatingroupA.AndnopatientshadendocrinedisordersingroupBCandDsuchasskinroughnessobesityhidrosisandetc.Conclusion:TranspositionofovaryassistedbyradiotherapyorHRTisagoodtherapyforyoungpatientswithendometrialcancer.[Keywords]Endometrial