复元胶囊对气虚血瘀证患者的临床疗效评价.docx

复元胶囊对气虚血瘀证患者的临床疗效评价[摘要]目的：探讨复元胶囊对气虚血瘀证患者症状、血液流变学及心功能的影响。方法：54例气虚血瘀证患者分为治疗组和对照组各27例对照组应用西药常规治疗治疗组在常规治疗基础上加用复元胶囊治疗每次5粒每日3次疗程1个月。分别观察两组治疗前后症状、血液流变学及心功能指标。结果：治疗组在治疗后症状、血液流变学及心功能指标均较对照组有显著改善(P＜0.05或P＜0.01)。结论：复元胶囊对气虚血瘀证患者症状、血液流变学及心功能有显著改善。[关键词]复元胶囊；气虚；血瘀；血液流变学；心功能[中图分类号]R969.4[文献标识码]B[文章编号]1673-7210（2008）04（c）-051-03EvaluatetheclinicalcurativeeffectofFuyuancapsuleinpatientswithqideficiencyandbloodstasisHUWen-xingLIRong-heng(DepartmentofIntegrationofTraditionalandWesternMedicinetheFirstAffiliatedHospitalChongqingMedicalUniversityChongqing400016China)[Abstract]Objective:ToexploretheinfluenceofFuyuancapsuletreatmentinpatientswithqideficiencyandbloodstasis.Methods:54caseswithqideficiencyandbloodstasisweredividedintotwogroupstheFuyuancapsulegroupandthecontrolgroupbesidesbasicdiseasesweretreatedintwogroupsthepatientsinFuyuancapsulegroupweretreatedwithFuyuancapsules.Scoresofsymptomandindexesofhemorheologyandheartfunctionweretestedafteramonth．Thedatawerecomparedwiththatofpre-therapy.Results:Thescoresofsymptomsweresignificantlylowerthanthoseofthecontrolgroup(P＜0.05orP＜0.01)theindexesofhemorheologywereimprovedsignificantlythanthoseofcontrolgroup(P＜0.05orP＜0.01)andtheindexesofheartfunctionweresignificantlyhigherthanthoseofcontrolgroup(P＜0.05orP＜0.01)．Conclusion:Fuyuancapsuletreatmentcanlessensymptomsreducebloodviscosityandenhanceheartfunctionofpatientswithqideficiencyandbloodstasis[Keywords]Fuyuancapsule;Qideficiency;Bloodstasis;Hemorheology;Heartfunction老年人常伴气虚气为血帅血为气母气行则血行气滞则血瘀因此气虚血瘀为老年病的常见病因常见于冠心病、肺心病、糖尿病等老年病。其预后很差给家庭和社会带来巨大的经济负担。因此积极防治气虚血瘀提高患者生活质量降低死亡率已成为国际老年病领域急需解决的难题。复元胶囊是以益气、活血、补肾药组成的中药制剂。本试验就其对气虚血瘀证患者临床症状、血液流变学、心功能的影响进行研究为该药的临床应用提供依据。1资料与方法1.1试验对象及分组54例均为我院门诊及住院患者均符合《中药新药临床研究指导原则》2005年版制定的气虚证症状分级量化标准及血瘀证症状分级量化标准气虚证积分值≥7分血瘀证