基于数据挖掘的《证治汇补》治疗脾胃病用药规律研究.pdf

基于数据挖掘的《证治汇补》治疗脾胃病用药规律研究王嘉芮喻斌【摘要】目的：基于数据挖掘研究《证治汇补》治疗脾胃病的用药规律以期为中医治疗脾胃病提供依据。方法：运用中医传承辅助平台V2.5软件对《证治汇补》中治疗脾胃病的有效方剂进行性味归经分布、频次统计、组方规律、核心组合、新方的分析。结果：共收集有效方剂137首涉及中药159味使用频次≥10的药物25味以性温、味辛、归脾经类药物最多;支持度个数设置为18置信数为0.6得到常用药对及组合15个;基于软件复杂熵层次聚类方法得到用于新方聚类的核心组合32组聚合成新方16首。结论：《证治汇补》中治疗脾胃病以温补脾阳为主用药方面以辛温药升阳行气为主辅以甘性药滋补和中、调和药性。【关键词】李用粹;《证治汇补》;中医传承辅助平台;脾胃病;用药规律【中图分类号】R256.3【文献标志码】A【文章编号】1007-8517（2020）4-0005-04StudyontheRuleofDrugsforTreatingSpleenandStomachDiseasesBasedonDataMininginZhengZhiHuiBuWANGjiarui1YUbin121.HunanUniversityofChineseMedicineChangsha410000China;2.DepartmentofSpleenandGastroenterologytheFirstAffiliatedHospitalofHunanUniversityofChineseMedicineChangsha410000ChinaAbstract：ObjectiveTostudytheruleoftreatmentofspleenandstomachdiseasesbasedondatamininginZhengZhiHuiBuinordertoprovideabasisforChinesemedicinetreatmentofspleenandstomachdiseases.MethodsTheeffectiveprescriptionofspleenandstomachdiseaseinthetreatmentofspleenandstomachdiseaseinthetreatmentofspleenandstomachdiseasewascarriedoutbyusingtheV2.5softwareofTCMinheritanceplatformtoanalyzethedistributionofsexualtastefrequencystatisticsprescriptionlawcorecombinationandnewprescription.ResultsAtotalof137effectiveprescriptionswerecollectedinvolving159flavorsoftraditionalChinesemedicine.25drugswithfrequency≥10wereusedandthemostcommondrugswerewenxinandspleen.Thenumberofsupportwassetto18andtheconfidencewas0.6.15commondrugpairsandcombinationswereobtained;basedonthesoftwarecomplexentropyhierarchicalclusteringmethod32coregroupsforclusteringofnewpartieswereobtainedand16newpartieswereaggregated.ConclusionThetreatmentofspleenandstomachdiseaseinthetreatment