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祝同学们新年学习(xuéxí)进步!圆圆满满!Chapter1RespiratoryPhysiologyVocabularyvocabularyupperairway:上呼吸道(shànghūxīdào)lung:肺pharynx:咽larynx:喉trachea:气管bronchi:支气管terminalbronchioles:终末支气管respiratorybronchioles:呼吸性支气管alveolar:肺泡intrapleuralpressure:胸内压functionalresidualcapacity(FRC):机能余气量vitalcapacity(VC):肺活量forcedvitalcapacity(VC):用力(yònglì)肺活量residualvolume(RV):余气量totallungcapacity(TLC):肺总容量closingcapacity(CC):闭合容量theminuteventilation:每分通气量arterialcarbondioxidetension:动脉血二氧化碳分压arterialoxygentension:动脉血氧分压cerebrospinalfluid:脑脊液peripheralchemoreceptor:外周化学(huàxué)感受器centralchemoreceptor:中枢化学感受器respiratoryreflex:呼吸反射laryngospasm:喉痉孪airwayobstruction:气道阻塞compliance:顺应性surfactant:表面活性物质surfacetension:表面张力(biǎomiànzhānglì)hypoxicpulmonaryvasoconstriction:缺氧性肺血管收缩deadspace:无效(wúxiào)腔anatomicaldeadspace:解剖无效腔respiratoryquotient:呼吸商oxyhaemoglobindissociationcurve:氧离曲线Haldaneeffect:Haldane效应Bohreffect:Bohr效应secondgaseffect:第二气体效应1.1.1LungFunctions肺通气肺换气(huànqì)气体运输组织换气氧化代谢LungFunctions1.1.2LungStructure鼻腔(bíqiāng)气管支气管细支气管终末细支气管呼吸(hūxī)性细支气管肺泡管肺泡囊肺泡(fèipào)内气体1.2ControlofRespiration中脑(zhōngnǎo)颈动脉体1.3MechanicsofRespiration1.3.1LungVolumes1.3.2ComplianceLawofLaplace:P:回缩压力P=2T/rT:肺泡(fèipào)表面张力r:肺泡半径Infactitdoesn’t!thepresenceofasurfaceactivematerialsecretedbythetypeIIalveolarcellsensuresthatthisdoesnotoccur.1.4MatchingofVentilationandPerfusion1.4.1DistributionofPerfusion1.4.2DistributionofVentilation1.4.3Ventilation:perfusionratioAnareaofthelungisperfusedbutinadequatelyventilatedVA/Qwillobviouslybereduced.AsaresultthealveolarPO2fallsandthePCO2rises.Wherealveoliareven