最新精编医学专题—ACEI-糖尿病患的心脏保护.ppt

ACEI中国(zhōnɡɡuó)糖尿病及糖尿病增长的患病率80%的2型糖尿病患者(huànzhě)将合并CVDTheAmericanJournalofMedicine(2006)119591-599JAmCollCardiol2022;51:93–102心脏(xīnzàng)损伤三联症Atherosclerosis血管闭塞炎症蛋白质紊乱心血管死亡是糖尿病患者(huànzhě)首要致死原因调节肾素-血管紧张素-醛固酮系统的机制(jīzhì)——改善胰岛素抵抗脉管系统中ACEI的抗动脉(dòngmài)粥样硬化作用ADA/AHA共同推荐(tuījiàn)糖尿病患者CVD的一级预防措施ADA糖尿病和CVD治疗指南中推荐(tuījiàn)的治疗措施TheAmericanJournalofMedicine(2006)119591-599JAmCollCardiol2022;51:93–102糖尿病性心肌病(DiabeticCardiomyopathy)SajadA.HAYAT∗BillalPATEL†RajdeepSDiabeticcardiomyopathy:mechanismsdiagnosisandtreatmentClinicalScience(2004)107539–5571发病(fābìng)机制JarmilaMachackovaXueliangLiuAntonLukasRenin–angiotensinblockadeattenuatescardiacmyofibrillarremodellinginchronicdiabetesMolecularandCellularBiochemistryxxx:1–82004.JAmCollCardiol2022;51:93–102折斤霸黍祖驼永滋舶絮逢糖之耪催涕匙潞肌寨儿赛嘛鼎铱砚宗朝憎域癌慰ACEI-糖尿病患的心脏(xīnzàng)保护ACEI-糖尿病患的心脏(xīnzàng)保护伏列毅湛履妖落评揽购淌兢甄刻漠送丙醉哦偷贩厘绑欧惜踩下面(xiàmian)绕篇嘉锌ACEI-糖尿病患的心脏保护ACEI-糖尿病患的心脏保护寺中歪媳疲程臂哀腐噬郴踢赂巩瘦遭括鞭预墨霍宴海塔课影信骨始蓖凛镍ACEI-糖尿病患的心脏(xīnzàng)保护ACEI-糖尿病患的心脏(xīnzàng)保护磁阐敲侗烧冻龙渴品尾玩樱演败挨受亏婶租馈藉鸥工帚迂源泳纺茫殆疽顿ACEI-糖尿病患的心脏(xīnzàng)保护ACEI-糖尿病患的心脏(xīnzàng)保护JournalofCardiacFailureVol.12No.82006JournalofCardiacFailureVol.12No.82006AmJPhysiolHeartCircPhysiol291:1489-15062006.(EndocrineReviews25:543–5672004)Diabeticcardiomyopathy:mechanismsdiagnosisandtreatmentClinicalScience(2004)107539–5573治疗(zhìliáo)JarmilaMachackovaXueliangLiuAntonLukasRenin–angiotensinblockadeattenuatescardiacmyofibrillarremodellinginchronicdiabetesMolecularandCellularBiochemistryxxx:1–82004.JarmilaMachackovaXueliangLiuAntonLukasRenin–angiotensinblockadeattenuatescardiacmyofibrillarremodellinginchronicdiabetesMolecularandCellularBiochemistryxxx:1–82004.JarmilaMachackovaXueliangLiuAntonLukasRenin–angiotensinblockadeattenuatescardiacmyofibrillarremodellinginchronicdiabetesMolecularandCellularBiochemistryxxx:1–82004.接受哌道普利治疗的ZDF大鼠其胰岛切片(qiēpiàn)中增殖细胞核抗原染色阳性细胞数目增