86例早期胃癌预后因素分析.docx

86例早期胃癌预后因素分析[摘要]目的:探讨分析对早期胃癌预后影响的因素。方法:回顾性分析1997年1月～2007年1月我院收治86例早期胃癌患者的临床资料及术后随访资料统计分析早期胃癌影响预后的因素。结果:本组早期胃癌病例5年生存率为90.9%其预后主要与肿瘤大小、淋巴结转移相关肿瘤直径4cm以上5年生存率分别为100.0%、71.6%50.5%有淋巴结转移者5年生存率(73.4%)明显低于无淋巴结转移者(91.3%)。相关性分析表明年龄、性别、病理分型与预后因素间无明显相关性。结论:毕Ⅰ或毕Ⅱ式根治术后患者淋巴结转移、肿瘤大小是早期胃癌重要的预后因素对肿瘤直径大、淋巴结转移广泛的早期胃癌患者应采用以根治术为主的综合治疗方案对指导早期胃癌预后及手术选择有实际应用价值。[关键词]早期胃癌;回顾性分析;预后[中图分类号]R735.207[文献标识码]A[文章编号]1673-7210(2010)01(b)-022-02Prognosticfactorsof86casesofearlygastriccancerWUBaoquan(DepartmentofSurgerytheAffiliatedHospitalofShandongMedicalCollegeLinyi276004China)[Abstract]Objective:Todiscussandanalyzethefactorsaffectingtheprognosisofearlygastriccancer.Methods:AretrospectiveanalysisfromJanuary1997toJanuary2007inourhospitaladmitted86casesofearlygastriccancerclinicaldataandpostoperativefollow-updatatostatisticalanalyzetheprognosticfactorsofearlygastriccancer.Results:5-yearsurvivalrateofearlygastriccancerinthisgroupwas90.9%theprognosisfactorsmainlyrelatedtotumorsizelymphnodemetastasisdiameter4cm5-yearsurvivalratewere100.0%71.6%50.5%respectivelyand5-yearsurvivalratewithlymphnodemetastasis(73.4%)waslowerthanthatwithoutlymphnodemetastasis(91.3%).Correlationanalysistableofagegenderpathologicalclassificationandprognosticfactorstherewasnosignificantcorrelation.Conclusion:Billroth'sⅠorⅡradicalsurgerypatientslymphnodemetastasistumorsizeareimportantprognosticfactorsinearlygastriccancerlymphnodemetastasisoftumordiameterlargerangeofearlygastriccancerwithradicalsurgeryshouldbebasedoncomprehensivetreatmentprogramandhavepracticalapplicationvaluetoguideearlygastriccancerprognosisandsurgicaloptions.[Keywords]Earlygastriccancer;Retrospectiveanalysis;Prognosis目前胃癌的发病率和死亡率仍居我国恶性肿瘤的首位。早期胃癌是1962年日本内镜学会提出的概念即癌灶不论有无淋巴结转移只浸润至胃黏膜层和黏膜下层[1]早期胃癌的预后分析在临床工作中很重要。本