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骨质疏松对股骨转子间骨折术后隐性失血的影响.docx

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骨质疏松对股骨转子间骨折术后隐性失血的影响 Title:TheImpactofOsteoporosisonOccultBloodLossafterIntertrochantericFractureSurgery Abstract: Osteoporosisisawidespreadskeletaldisordercharacterizedbylowbonedensityandstructuraldeteriorationofbonetissue,resultinginincreasedsusceptibilitytofractures.Intertrochantericfracturesofthefemurarecommoninelderlyindividualswithosteoporosis.Surgicaltreatment,likeinternalfixationwithadynamichipscreworintramedullarynailing,isoftenrequiredtorestorestabilityandfacilitatehealing.However,postoperativecomplicationssuchasoccultbloodlosscansignificantlyaffectpatientoutcomes.Thispaperaimstoexploretheimpactofosteoporosisonoccultbloodlossfollowingsurgeryforintertrochantericfractures,withanemphasisontheunderlyingmechanismsandpotentialstrategiestominimizeitsoccurrence. Introduction: Osteoporosisisaprogressiveskeletalconditioncharacterizedbyreducedbonestrengthandanincreasedriskoffractures.Itaffectsmillionsofindividualsglobally,predominantlywomenintheirpostmenopausalyears.Theprevalenceofintertrochantericfracturesissignificantlyhigherinpatientswithosteoporosisduetotheweakenedbonestructure.Surgicalintervention,suchasinternalfixation,isoftennecessarytorestoreanatomicalalignmentandallowearlymobilization. Occultbloodloss,aformofhiddenbloodlosswithoutobviousexternalbleeding,isacomplicationassociatedwithintertrochantericfracturesurgery.Whilethecausesofoccultbloodlossaremultifactorial,osteoporosis-relatedchangesinbonemicroarchitectureandvascularitylikelycontributetoincreasedbleedingduringandafterthesurgery.Understandingtheinfluenceofosteoporosisonoccultbloodlossfollowingintertrochantericfracturesurgeryiscrucialfordevelopingeffectivestrategiestominimizecomplicationsandimprovepatientoutcomes. MechanismsofOccultBloodLossinOsteoporoticPatients: 1.AlteredBoneMicroarchitecture:Osteoporoticbonesarecharacterizedbydecreasedtrabecularbonedensityandremodelingimbalance.Thecompromisedbonestructureleadstoimpairedvascularintegrityandincreasedsusceptibilitytobleedingduringsurgicalprocedures. 2.E