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结直肠癌术后中医药联合化疗临床疗效分析.docx

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结直肠癌术后中医药联合化疗临床疗效分析 Abstract Colorectalcancerisoneofthemostcommonmalignanttumorsintheworld,andsurgeryisstillthemaintreatment.However,theeffectofsurgeryaloneoncolorectalcancerislimited,anditisnecessarytoactivelyseekadjuvanttreatmentmeasurestoimprovetheprognosisofpatients.TraditionalChinesemedicine(TCM)hasthecharacteristicsofmulti-targetedandmulti-levelcomprehensivetreatment,andithasbeenprovedbyclinicalpracticethatTCMhasacertaineffectontheadjuvanttreatmentofcolorectalcancer.ThispaperanalyzestheclinicalefficacyofTCMcombinedwithchemotherapyintheadjuvanttreatmentofpostoperativecolorectalcancerandprovidesguidanceforclinicalpractice. Introduction Colorectalcancerisoneofthefourmajormalignanttumorsintheworld.Theincidenceandmortalityratesareincreasingyearbyyear,andithasbecomeamajorhealthproblemfacingsociety.Atpresent,surgeryisstillthemaintreatmentforcolorectalcancer,butitseffectislimited.Adjuvantchemotherapycanimprovetheprognosisofpatientswithcolorectalcancer,butitalsohasmanytoxicandsideeffects.TraditionalChinesemedicine(TCM)hasalonghistoryoftreatingcolorectalcancer.Duetoitsmulti-targeted,multi-levelandcomprehensivetreatmentcharacteristics,TCMhasacertaineffectontheadjuvanttreatmentofcolorectalcancer. Methods Theclinicaldataof80patientswithpostoperativecolorectalcancertreatedinourhospitalfromJanuary2019toJanuary2021wereretrospectivelyanalyzed.Thepatientswererandomlydividedintoacontrolgroupandatreatmentgroup,with40casesineachgroup.Thecontrolgroupreceivedstandardadjuvantchemotherapy,whilethetreatmentgroupreceivedTCMcombinedwithchemotherapy.Theclinicalefficacy,adversereactionsandqualityoflifeofthetwogroupswerecomparedandanalyzed. Results Theclinicalefficacyofthetreatmentgroupwassignificantlybetterthanthatofthecontrolgroup,andthedifferencewasstatisticallysignificant(P<0.05).Theincidenceofadversereactionsinthetreatmentgroupwassignificantlylowerthanthatinthecontrolgroup(P<0.05).Thequalityoflifescoreinthetreatmentgroupwassignificantlyhigherthanthatinthecontrolgroup(P<0.05).Thediffere