预览加载中,请您耐心等待几秒...
1/3
2/3
3/3

在线预览结束,喜欢就下载吧,查找使用更方便

如果您无法下载资料,请参考说明:

1、部分资料下载需要金币,请确保您的账户上有足够的金币

2、已购买过的文档,再次下载不重复扣费

3、资料包下载后请先用软件解压,在使用对应软件打开

多种分析方法测定邻氯代苯亚甲基丙二腈的纯度 Title:AComparativeAnalysisofMultipleMethodsforAssessingthePurityofChlorobenzylideneMalononitrile Abstract: Purityanalysisisanessentialstepindeterminingthequalityandperformanceofchemicalsubstances.Inthisstudy,weaimedtoevaluatethepurityofchlorobenzylidenemalononitrileusingmultipleanalyticalmethods.Fourdifferenttechniques,includingmeltingpointanalysis,thin-layerchromatography,gaschromatography,andspectroscopy,wereemployedforcomprehensiveevaluation.Theresultsobtainedfromeachmethodwerecomparedanddiscussedintermsofaccuracy,sensitivity,andapplicability.Overall,thisstudyprovidescriticalinsightsintotheviabilityofeachtechniquefordeterminingthepurityofchlorobenzylidenemalononitrile,thuscontributingtothedevelopmentofeffectivepurityassessmentprotocols. Introduction: Chlorobenzylidenemalononitrileisawidelyusedchemicalcompoundwithapplicationsinvariousindustries,includingpharmaceuticals,agrochemicals,andmaterialsscience.Ensuringthehighpurityofthiscompoundiscrucialtoguaranteeitssafetyandeffectivenessindifferentapplications.Purityanalysismethodsplayavitalroleinassessingthecomposition,concentration,andimpuritylevelspresentinasample. Methods: 1.MeltingPointAnalysis: Meltingpointanalysisisacommonlyusedinitialscreeningmethodforthedeterminationofsubstancepurity.Anarrowmeltingpointrangeindicatesahigherpuritylevel.Inthisstudy,themeltingpointofchlorobenzylidenemalononitrilewasdeterminedusingaMel-Tempmeltingpointapparatus. 2.Thin-LayerChromatography(TLC): TLCisaversatileseparationtechniquethatallowsfortheidentificationandmeasurementofdifferentcompounds.Asilicagel-coatedplatewasusedinthisstudy,withamobilephaseconsistingofamixtureofhexaneandethylacetate.Visualizationwasdoneusingiodinevapor,andRfvalueswerecalculatedtodeterminethepurityofthetargetcompound. 3.GasChromatography(GC): GCisawidelyusedtechniqueforseparating,analyzing,andquantifyingvolatilecompounds.AGC-FID(GasChromatograph-FlameIonizationDetector)systemwasusedtoanalyzethepurityofchlorobenzylidenemalononitrile.Thes