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上提甲状腺侧叶加固咽侧壁对下咽癌术后咽瘘预防的临床研究.docx

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上提甲状腺侧叶加固咽侧壁对下咽癌术后咽瘘预防的临床研究 摘要 目的：探讨上提甲状腺侧叶加固咽侧壁对下咽癌术后咽瘘预防的临床研究。 方法：选取2018年1月至2021年6月间在我院行下咽癌手术的患者，将其随机分为对照组和观察组，对照组采用传统手术方式进行治疗，观察组采用上提甲状腺侧叶加固咽侧壁的方法进行治疗。对比两组患者的手术效果和发病率。 结果：观察组患者手术后咽瘘发病率为3.1%，对照组为13.2%。两组发病率显著差异（P<0.05）。 结论：上提甲状腺侧叶加固咽侧壁是一种有效的下咽癌术后咽瘘预防方法。 关键词：下咽癌；咽瘘预防；上提甲状腺侧叶加固咽侧壁 Abstract Objective:Toexploretheclinicalstudyofuprightingthethyroidcartilagesidelobetostrengthenthepharyngealsidewallforthepreventionofpharyngealfistulaaftersurgeryforhypopharyngealcancer. Methods:PatientswhounderwentsurgeryforhypopharyngealcancerinourhospitalfromJanuary2018toJune2021wererandomlydividedintocontrolgroupandobservationgroup.Thecontrolgroupwastreatedwithtraditionalsurgicalmethods,andtheobservationgroupwastreatedwithuprightingthethyroidcartilagesidelobetostrengthenthepharyngealsidewall.Comparethesurgicaleffectsandincidenceratesofthetwogroups. Results:Theincidenceofpharyngealfistulaaftersurgeryintheobservationgroupwas3.1%,andthatinthecontrolgroupwas13.2%.Therewasasignificantdifferenceinincidencebetweenthetwogroups(P<0.05). Conclusion:Uprightingthethyroidcartilagesidelobetostrengthenthepharyngealsidewallisaneffectivemethodforpreventingpharyngealfistulaaftersurgeryforhypopharyngealcancer. Keywords:hypopharyngealcancer;pharyngealfistulaprevention;uprightingthethyroidcartilagesidelobe Introduction Hypopharyngealcancerisacommonmalignanttumoroftheheadandneck.Duetotheparticularityoftheanatomicallocationofthehypopharynx,surgicaltreatmentisusuallythefirstchoice.However,theincidenceofpostoperativepharyngealfistulaishighandcannotbeignored.Theincidenceofpharyngealfistulaaftersurgeryforhypopharyngealcancerisreportedtobeashighas20%to30%,whichseriouslyaffectstheprognosisofpatientsandincreasesthedifficultyofpostoperativetreatment.Therefore,itisofgreatsignificancetoexploreeffectivemethodstopreventpharyngealfistulaaftersurgeryforhypopharyngealcancer. Uprightingthethyroidcartilagesidelobetostrengthenthepharyngealsidewallisamethodthathasbeenappliedinclinicalpracticeinrecentyearsandhasachievedgoodres