软胶囊囊壳材料的研究概况.pdf

2007,Vol.31,No.11491·综述与专论·
ProgressinPharmaceuticalSciences2007年第31卷第11期

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软胶囊囊壳材料的研究概况

郑文杰1,刘建平13,陈华东2

(1.中国药科大学药物制剂研究所,江苏南京210009;2.上海长海医院药学部,上海200433)

[摘要]分类概述软胶囊囊壳材料的理化性质及对软胶囊稳定性的影响,其中包括明胶和各种替代材料以及非
胶体材料(如增塑剂、抗氧化剂等添加剂)。
[关键词]软胶囊;囊壳材料;胶体材料;明胶;理化性质;交联反应;稳定性
[中图分类号]R94415;TQ46014[文献标识码]A[文章编号]1001-5094(2007)11-0491-05

AnOverviewonSoftCapsuleShellCompositions

ZHENGWen2jie1,LIUJian2ping1,CHENHua2dong2

(1.InstituteofPharmaceutics,ChinaPharmaceuticalUniversity,Nanjing210009,China;2.De2partmentof
Pharmacy,ChangHaiHospitalofShanghai,Shanghai200433,China)

[Abstract]Thephysico2chemicalpropertiesofsoftcapsuleshellcompositions,includinggelatin,gelatin
substitutesandnon2gellingmaterialssuchasplasticizer,anti2oxidantandsoon,andtheireffectsonstability
ofsoftcapsulesweresummarized