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·4861·辽宁中医杂志2014年第41卷第8期 DOI∶10.13192/j.issn.1000-1719.2014.08.054 清肝泻火法治疗甲状腺功能亢进症的临床研究 郑仲华1,曾庆明2 (1.郑州市中医院糖尿病科,河南郑州450007;2.桐柏县卫生学校,河南桐柏县474750) 摘要:目的:观察清肝泻火法治疗肝火旺盛型甲状腺功能亢进症的临床疗效。方法:将甲亢患者60例采用随机数 字表法随机分为治疗组和对照组各30例。两组病例均采用常规西医治疗,口服他巴唑片,治疗组在常规治疗基础上加 服中药,30d为1个疗程,治疗3个疗程。结果:治疗组总有效率93.33%,对照组总有效率83.33%,两组对比,差别有统 计学意义(P<0.05);两组均可调节甲状腺激素水平,与治疗前相比,差别有统计学意义(P<0.01),治疗后两组对比,差 别有统计学意义(P<0.05或P<0.01);治疗组在改善中医临床症状,减少副反应方面,疗效优于对照组,差别有统计学 意义(P<0.05)。结论:清肝泻火法能够调节甲状腺素水平、改善中医症状和体征、减少不良反应,比单纯西药治疗甲亢 疗效显著。 关键词:甲亢;辨证;肝火旺盛;清肝泻火 中图分类号:R581.1文献标志码:B文章编号:1000-1719(2014)08-1684-03 ClinicalObservationonLiver-clearingandFire-purgingTherapyofHyperthyroidism ZHENGZhonghua1,ZENGQingMing2 (1.ZhengzhouHospitalofTCM,Zhengzhou450007,He'nan,China; 2.TongbaiCountrYMedicalSchool,Tongbai474750,He'nan,China) Abstract:Objective:ToobservetheclinicalefficacYofliver-clearingandfire-purgingtherapYofhYperthYroidisM.Meth- ods:60patientswithhYperthYroidisMusingrandoMnuMbertableswererandoMlYdividedintotreatMentandcontrolgroupswith30 patientsineach.BothgroupsweretreatedwithconventionalWesternMedicine,oraladMinistrationofMethiMazoletablets.The treatMentgroupaddedtraditionalChineseMedicinetreatMent.30daYswasacourseoftreatMent,andthetreatMentlastedfor3 courses.Results:TreatMentgroup'stotaleffectiverate93.33%andthecontrolgroup'swas83.33%.Therewasstatisticaldiffer- encebetweentwogroups(P<0.05).TwogroupsbothcanregulatethethYroidhorMonelevelandtherewasstatisticaldifference aftertreatMentintwogroups(P<0.01).AftertreatMent,thetwogroupshadstatisticaldifference(P<0.05orP<0.01). TreatMentgroupwassuperiortocontrolgroupiniMprovingTCMclinicalsYMptoMsaswellasreducingsideeffectsandthediffer- encehadstatisticsMeaning(P<0.05).Conclusion:Liver-clearingandfire-purgingtherapYcanregulatethethYroidhorMone levels,iMprovethesYMptoMsandsignsoftraditionalChineseMedicineandreduceadversereactionsanditissuperiortoWestern MedicinetreatMentofhYperthYroidisM. Keywords:hYperthYroidisM;sYndroMedifferentiation;liver-fireexcess;clearingliveran