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JournalofZhengzhouUniversity(MedicalSciences)Nov.2008Vo1.43No.6·1l95· [3]李洁,周灿权,钟依平,等.低剂量GnRHa在IVF—ET中的[7]BormG,MannaertsB.Treatmentwiththegonadotrophin—re— 应用之三长效1.3mgGnRHa与短效GnRHa长方降调节leasinghormoneantagonistganirelixinwomenundergoing 的比较[J].中华现代妇产科学杂志,2004,1(1):40ovarianstimulationwithrecombinantfolliclestimulating [4]LudwigM,FelberbaumRE,DevroeyP,eta1.Significantre—hormoneiseffective.safeandconvenient:resultsofacon— ductionoftheincidenceofovarianhyperstimulationsyn—trolled,randomized,muhicentretrial[J].HumReprod, drome(OHSS)byusingtheLHRHantagonistCetrorelix2000,15(7):1490 (Cetrotide)incontrolledovarianstimulationforassisted[8]AlbanoC,FelberbaumRE,SmitzJ,etalOvarianstimulation reproduction[J].ArchGynecolObstet,2000,264(1):29withHMG:resultsofaprospectiverandomizedphaseⅢEu— [5]CheungLP,LamPM,LokIH,eta1.GnRHantagonistver—ropeanstudycomparingtheluteinizinghormone·releasing SUSlongGnRHagonistprotocolinpoorrespondersunder—hormone(LHRH)一antagonistcetrorelixandtheLHRH—ago— goingIVF:arandomizedcontrolledtrial[J].HumReprod,nistbuserelin[J].HumReprod,2000,15(3):526 2005,20(3):616[9]RombautsL,HealyD,NormanRJ,eta1.Acomparative [6]DePlacidoG,MolloA,ClariziaR,eta1.Gonadotropin—re—randomizedtrialtoassesstheimpactoforalcontraceptive leasinghormone(GnRH)antagonistplusrecomebinantlu—pretreatmentonfolliculargrowthandhormoneprofilesin teinizinghormonesastandardGnRHagonistshortproto—GnRHantagonist—treatedpatients[J].HumReprod,2006, colinpatientsatriskforpoorovarianresponse[J].Fertil21(1):95 Steril,2006,85(1):247(2008-02-01收稿责任编辑姜春霞) 2型糖尿病并冠心病患者血清脂联素水平测定 张苏河△李青菊辛雅萍陈璐璐 1)华中科技大学同济医学院附属协和医院内分泌科武汉4300222)郑卅I大学第二附属医院内分泌科郑州450014 △女,52岁,博士生,主任医师,研究方向:糖尿病及其并发症防治 关键词脂联素;2型糖尿病;冠心病 中图分类号R587.1 摘要目的:探讨脂联素(ADPN)与2型糖尿病并发冠心病的关系。方法:采用ELISA法测定35例健康体检 者(正常对照组)、40例单纯2型糖尿病(T2DM组)及37例糖尿病并冠心病患者(DM—CHD组)血清ADPN及肿瘤 坏死因子一ot(TNF—o【)水平。结果:正常对照组、T2DM组和DM—CHD组血清ADPN水平分别为(1O.51±2.77), (7.51±3.19)和(4.94±3.57)mg/L,依次降低(P<0.05);TNF—d水平分别为(0.96±0.27),(1.20±0.22)和 (1.54±0.30)ng/L,依次升高(P<0.01)。糖尿病并冠心病患者ADPN水平与TNF