幽门螺杆菌在健康人群体检中感染状况的调查分析.pdf

幽门螺杆菌在健康人群体检中感染状况的调查分析目的調查幽门螺杆菌（Hp）在健康人群体检中的感染状况，分析Hp感染相关影响因素，提出对策。方法抽取2016年1月～2017年1月来我院体检的235例健康体检者作为研究对象，采取碳14呼气卡实验方式对体检者进行Hp感染情况调查，同时采用自制问卷对体检者日常情况加以调查，观察指标包括健康体检者发生Hp感染情况、Hp感染相关因素、不同年龄段体检者Hp感染情况。结果235例健康体检者中发生Hp检测呈阳性者共计115例，占比48.94%；年龄≥50岁群体Hp感染率为56.67%，明显高于年龄0.05）。经多因素分析，吸烟（OR=9.943，P=0.045）和年龄≥50岁（OR=6.132，P=0.039）为健康人群发生Hp感染的独立危险因素。结论健康人群Hp感染与不良生活习性、糖尿病史、冠心病史、年龄因素关联密切，其中吸烟和年龄≥50岁是健康人群发生Hp感染的独立危险因素。[Abstract]ObjectiveToinvestigatetheinfectionstatusofHelicobacterpylori（Hp）inhealthypeople，analyzeHpinfection-relatedinfluencingfactors，andputforwardcountermeasures.MethodsAtotalof235healthysubjectswhoweregivenphysicalexaminationfromJanuary2016toJanuary2017wererandomlyselectedassubjects.Carbon-14breathcardtestmethodwasadoptedforallhealthsubjectstoconductHpinfectionsurvey.Atthesametime，self-madequestionnairewasusedforthesubjectstoconductdailysituations.TheobservationindicatorsincludedtheoccurrenceofHpinfectioninhealthysubjects，Hpinfection-relatedfactors，Hpinfectionsindifferentagegroups.ResultsAtotalof115patientswithpositiveHpweredetectedin235healthysubjects，accountingfor48.94%，theinfectionrateofHpwas56.67%intheagegroup≥50yearsold，whichwassignificantlyhigherthanthatintheagegroup＜50yearsold（35.29%）（P＜0.05）；theinfectionrateofHpwas65.93%inthedrinkingpopulation，whichwassignificantlyhigherthanthatof26%insmalldrinkingamountornon-drinkingpopulation（P＜0.05）；theinfectionrateofHpinsmokingpopulationwas60.39%，whichwassignificantlyhigherthanthatof27.16%innon-smokers（P＜0.05）；theinfectionrateofHpinpatientswithcoronaryheartdiseaseanddiabetesmellituswassignificantlyhigherthanthatinpatientswithoutcoronaryheartdiseaseanddiabetesmellitus，thedifferencewasstatisticallysignificant（P＜0.05）.TheinfectionrateofHpinhypertensivepopulationwas49.19%，andtheinfectionratewas50.81%innon-hypertensivepopulation.Therewasnosignificantdifference（P>0.05）.Afteramultivariateanalysis，itwasfoundthatsmoking（OR=9.943，P=0.045）andage≥50yearsold（OR=6.132，P=0.039）wereindependentriskfactorsforHpinfectioninhealthysubjec