欣可聆预防人流术后宫腔粘连的临床研究.docx

欣可聆预防人流术后宫腔粘连的临床研究[摘要]目的分析透明质酸钠凝胶在人工流产术后宫腔粘连中的预防应用及效果。方法选择在笔者所在医院行人工流产术患者500例随机分为对照组和治疗组两组各250例。对照组行常规人工流产术实验组在人工流产术后宫腔内注医用透明质酸钠凝胶。两组术后均常规给予抗生素及益母草制剂服用。术后定期随访观察两组术后有无粘连。结果治疗组术后宫腔粘连发生率明显低于对照组差异有统计学意义（P<0.05）。同一年龄段两组宫腔粘连发生情况比较差异有统计学意义（P<0.05）。结论人工流产术后宫腔内注入透明质酸钠凝胶具有减少宫腔粘连发生、不良反应少等优点值得在临床推广应用。[关键词]透明质酸钠凝胶；人工流产；宫腔粘连[中图分类号]R169.4[文献标识码]B[文章编号]1673-9701（2013）07-0151-03PreventionofhighconcentrationofmedicalsodiumhyaluronategelinthetreatmentofintrauterineadhesionsafterabortionSHENBingqiuFertilitySectiontheMaternalandChildHealthHospitalofJiaxingCityinZhejiangProvinceJiaxing314000China[Abstract]ObjectiveToanalyzeoftheapplicationandeffectsofhyaluronicacidinthepreventionofintrauterineadhesionsafterabortion.MethodsAtotalof500patientsundergoingabortiontechniqueoftheauthor’shospitalwererandomlydividedintotwogroupsofcontrolgroupandthetreatmentgroupwith250casesofeachgroup.Thecontrolgroupwastreatedwithconventionalartificialabortionandtheexperimentalgroupwastreatedwithintrauterineinjectionofsodiumhyaluronateafterabortion.Twogroupswereroutinelygivenantibioticsandmotherwortpreparationsafteroperation.Twogroupswerefollowedupregularafteroperationsurgeryandtestedadhesions.ResultsIncidenceofintrauterineadhesionsafteroperationoftreatmentgroupweresignificantlylowerthanthoseinthecontrolgroupandthedifferencewasstatisticallysignificant（P<0.05）.Thedifferenceofthetwogroupsinthesameageintrauterineadhesionswasstatisticallysignificant（P<0.05）.Comparedwiththecontrolgroupmenstruationafteroperationoftreatmentgroupwerebetter.Thedifferencewasstatisticallysignificant（P0.05）具有可比性。1.2方法对照组：采用常规无痛人工流产术。治疗组：采用常规无痛人工流产术在无痛人工流产术全部做结束后吸宫干净后用特制的一根长15cm、内径2mm的无菌塑料宫腔灌注导管将医用透明质酸钠凝胶宫腔内灌注至宫底部平卧1h。两组术后均常规给予抗生素及益母草制剂服用。1.3观察指标及评价标准[3]术后不均行宫腔镜检查一般行