早期胃癌临床病理特征与淋巴结转移的相关分析.docx

早期胃癌临床病理特征与淋巴结转移的相关分析[摘要]目的探讨早期胃癌所具有的临床病理特征并分析临床病理特征和淋巴结转移之间的相关性。方法择取2011年1月～2012年1月于本院治疗的160例早期胃癌患者全部经过病理诊断确诊。按照术后是否发生淋巴结转移来分组：发生淋巴结转移的80例患者为研究组未发生淋巴结转移的80例患者为对照组。分析两组患者之间存在的差异因素并对比两组患者的5年存活率。结果两组患者在肿瘤体积、组织学分型、肿瘤浸润程度、脉管侵犯程度上有明显的差异可见上述因素与淋巴结转移之间存在着一定的联系；而就5年存活率而言对照组为97.50%（78/80）研究组为87.50%（70/80）研究组低于对照组差异有统计学意义（P[关键词]早期胃癌；临床病理特征；淋巴结转移；相关性[中图分类号]R735.2[文献标识码]B[文章编号]1673-9701（2017）11-0094-03CorrelativeanalysisofclinicopathologicalfeaturesandlymphnodemetastasisinearlygastriccancerLiDandanDepartmentofPathologyZaozhuangMiningGroupTengnanHospitalJi’ning277606China[Abstract]ObjectiveToexploretheclinicopathologicalfeaturesofearlygastriccancerandtoanalyzethecorrelationbetweenclinicopathologicalfeaturesandlymphnodemetastasis.Methods160patientswithearlygastriccancertreatedinourhospitalfromJanuary2011toJanuary2012wereselectedallthroughthepathologicaldiagnosisofpositiveresults.Thepatientsweredividedintotwogroups.80patientswithlymphnodemetastaseswereincludedinthestudygroupand80patientswithoutlymphnodemetastasiswereincludedinthecontrolgroup.Thedifferencesbetweenthetwogroupswereanalyzedandthefive-yearsurvivalratewascomparedbetweenthetwogroups.ResultsThereweresignificantdifferencesintumorvolumehistologicaltypedegreeoftumorinfiltrationanddegreeofvascularinvasionbetweenthetwogroups.Anditcouldbelearnedthattherewasacertainrelationshipbetweentheabovefactorsandlymphnodemetastasis.Intermsofthefive-yearsurvivalratethecontrolgroupwas97.50%（78/80）higherthan87.50%（70/80）ofthestudygroupwithstatisticaldifference（P[Keywords]Earlygastriccancer；Clinicopathologicalfeatures；Lymphnodemetastasis；Relevance早期胃癌多分布在胃黏膜与胃黏膜下层近些年来由于病理检查和胃镜检查技术的不断发展早期胃癌的检出率正在不断提高[1]。事实上与进展期胃癌相比早期胃癌具有更好的预后效果但是无法避免的是一些患者依然在术后发生了淋巴结转移问题而是否存在淋巴结转移直接关系到患者的预后结果和生存期限[2]。本