太子参等3种中药材中铜-铅-砷-汞-镉含量的分析研究.docx

太子参等3种中药材中铜\铅\砷\汞\镉含量的分析研究[摘要]目的:建立太子参等3种药材中铜、铅、砷、汞、镉含量测定方法。方法:根据元素特性选择不同消解方法采用火焰法测定Cu的含量石墨炉法测定Pb、Cd的含量结合氢化物发生器测定As、Hg的含量土壤采用送外检的方式追溯其生长环境对中药材中重金属含量的影响。结果:以太子参药材建立的方法稳定精密度Cu为0.30%Pb为5.30%Hg为1.60%Cd为2.90%As为1.80%;回收率Cu为98.00%(RSD=1.60%)Pb为90.00%(RSD=1.20%)As为83.00%(RSD=1.20%)Hg为93.00%(RSD=3.60%)Cd为90.00%(RSD=3.60%)同时药材生长的土壤对其重金属残留量有一定的影响。结论:本文为该类药材中Cu、Pb、As、Hg、Cd的含量测定提供了可靠的检测方法为其质量标准的制订提供了科学依据。[关健词]中药材;重金属;原子吸收分光光度计;氢化物发生器[中图分类号]R927.2[文献标识码]B[文章编号]1673-7210(2010)04(a)-078-03StudyoncontentdeterminationofCuPbAsHgandCdinTaizishenandtheothertwokindsofChineseherbalmedicineXIONGXianhongCHENXiaorongCHENHua(RiverPharmaceuticalCo.Ltd.Nanchang330077China)[Abstract]Objective:ToestablishamethodforthecontentdeterminationofCuPbAsHgandCdinTaizishenandtheothertwokindsofChineseherbalmedicine.Methods:AccordingtotwolawelementofchoiceofdifferentdryandwetdigestionherbsusingtheflamemethodwithCucontentmeasuredmeasuringPbCdcontentbygraphitefurnacemethodcombinedwithhydridegeneratordeterminedAsHgcontentusingthesoiltosendexternalreviewofthewaybackthegrowthofheavymetalsinsoilonthecontentofChineseherbalmedicines.Results:HeterophyllamedicinalmethodsinordertoestablishastableprecisionforCuis0.30%Pbis5.30%Asis1.80%Hgis1.60%Cdis2.90%andtherecoveryforCuis98.00%(RSD=1.60%)Pbis90.00%(RSD=1.20%)Asis83.00%(RSD=1.20%)Hgis93.00%(RSD=3.60%)Cdis90.00%(RSD=3.60%)whilethegrowthofmedicinalresiduesinsoilheavymetalshaveacertainimpact.Conclusion:ThistypeofmedicinecontentdeterminationfortheCuPbAsHgCdprovideareliabledetectionmethodforthedevelopmentofqualitystandardsprovideascientificbasis.[Keywords]Chineseherbalmedicine;Heavymetal;Atomicabsorptionspectrophotometer;Hydridegenerator中药材中重金属含量多少直接反应药材的质量由于药材的产地、栽培及加工条件不同使药材中所含Cu、Pb、As、Hg