绝经后骨质疏松症生存质量和中医证型的初步研究.doc

绝经后骨质疏松症生存质量和中医证型的初步研究
绝经后骨质疏松症生存质量和中医证型的初步研究
更新日期：2009-07-14点击：邵敏庄洪宋文昭

提要为了解绝经后骨质疏松症患者的生存质量及其与中医证型间的关系。共对421名社区绝经后妇女进行腰椎双能X线扫描测定骨密度，利用SF-36生存质量调查量表和中医证候调查表进行了生存质量和中医证型调查。结果示421名绝经后妇女中骨质疏松症的发病率为60%，与文献记录相近。绝经后骨质疏松症患者生存质量低于非骨质疏松症患者。在中医证型的调查中发现，全组妇女肾虚的发病率最高，达73.3%，其次为心虚、肝虚和脾虚，发病率达58.6%、54.5%和39.2%，气虚、阴虚、血瘀、阳虚的发病率亦较高，分别为36.4%、32.3%、20.2%、18.8%，而肺虚、血虚的发病率相对较低，不足10%。而在骨质疏松症患者中以上各证的发病率均升高，其中肾虚发病率达84.7%，多合心虚、肝虚和脾虚，复合发病率分别达62.7%、61.0%和50.1%。表明绝经后骨质疏松症患者的生存质量与正常同龄人相比下降，该病患者中医证型以肾虚为主，同时兼有心虚、肝虚和脾虚。生存质量和中医证型进一步的研究有可能引入骨质疏松症的诊断与疗效评价。
主题词骨质疏松症/病理学骨密度骨质疏松症/分类中医证型生存质量调查研究
中图分类号R255；R365文献标识码：A文章编号：1001-6015(2000)05-0009-02

THESURVIVALQUALITYINPOSTMENOPAUSALOSTEOPOROSISANDITSTCMSYNDROMESTYPING:APrimaryStudy

ShaoMin，ZhuangHong，SongWenzhao
（GuangzhouUniversityofTraditionalChineseMedicine,Guangzhou510405）

TostudythesurvivalqualityofpatientswithpostmenopausalosteoporosisanditsrelationtoTCMsyndromestyping,bonemineraldensities(BMD)of421postmenopausalwomenweremeasuredbydouble-energyX-rayscanningofthelumbarvertebrae,andthesurvivalqualityandTCMsyndromestypingofthepatientswereinvestigatedbysurvival-qualityandTCM-syndromesquestionaires.Theresultsshowed:(1)Theosteoporosisincidenceofthe421patientswas60%,whichisnearthatreportedintheliterature;(2)Thesurvivalqualityofthepostmenopausalpatientswithosteoporosiswaslowerthanthatofnon-osteoporosispatients;(3)TheinvestigationofTCMsyndromestypingrevealedthatinallwomenofthisgroup,thekidney-deficiencyincidencewasthehighest(73..3%),thenextwastheincidencesofheartdeficiency,liverdeficiencyandspleendeficiency(58.6%,54.5%and39.2%);theincidencesofQideficiency,Yindeficiency,bloodstasisandYangdeficiencywerehigh,too(36.4%,32.3%,20.2%and18,.8%),whiletheincidencesoflungdeficiencyandblooddeficiencywererelativelylow(under10%);Theincidencesofalltheabovesyndromesoftheosteoporosispatientswereraised,amongwhichthekidney-deficiencyincidencereached84.7%,whichwasfrequentlycomplicatedwithheartdeficiency,liverdeficiencyandspleendeficiency(compositeincidences:62.7%,61.0%and50.1