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基于LabVIEW的OCT信号采集和分析 I.Introduction OpticalCoherenceTomography(OCT)isaninnovativeandnon-invasiveimagingtechniquethathasenjoyedwidespreadapplicationinmedicaldiagnostics,industrialimaging,andmaterialsscience.Thetechniqueuseslow-coherenceinterferometrytoproduceimagesofbiologicaltissueswithunparalleledresolution.OneoftheessentialcomponentsofanOCTsystemisthesignalacquisitionandanalysissubsystem,whichfunctionstocollect,process,andinterpretOCTsignals.LabVIEWisapowerfulprogrammingenvironmentthatcanbeusedtodevelophighlyefficientandflexiblesignalacquisitionandanalysissubsystemsforOCTsystems.ThispaperpresentsadiscussionoftheuseofLabVIEWforOCTsignalacquisitionandanalysis. II.LabVIEWProgrammingEnvironment LabVIEWisagraphicalprogrammingenvironmentthatusesblockdiagramstorepresentprogramcodevisually.Thetoolsetprovidesdesignerswithawidearrayofpre-builtfunctionsandtoolsfordevelopingcomplexapplications.Thehigh-leveldataflowprogrammingmodeladoptedbyLabVIEWenablesthecreationofintuitivelyunderstandablesoftwareapplicationswithwell-definedinputandoutputbehaviors.BecauseLabVIEWisadataflowprogramminglanguage,itissuitablefortime-basedsignalanalysis,makingitidealforOCTsignalacquisitionandanalysis. III.BasicelementsofanOCTmeasurementsystem ThebasicelementsofanOCTmeasurementsystemincludealightsource,referencearm,samplearm,detectionsystem,signalacquisitionandanalysissubsystem,anddisplaymonitor(Figure1).Theopticalsignalisgeneratedbythelightsourceandsplitintotwobeams.Onebeamservesasthereference,whiletheotherpassesthroughthesample.Thebackscatteredlightfromthesampleinteractswiththereferencebeamatthedetector,leadingtothecreationofaninterferencefringepattern.Thesignalisthencapturedbythedetectorandpassedthroughthesignalacquisitionandanalysissubsystembeforedisplayonthemonitor. IV.OCTSignalAcquisition OCTsignalsaretypicallyweakandrequirecarefulacquisitiontoavoidinterferencefromnoise.ThetraditionalmethodofacquiringanOCTsignalisthroughtime-domainacquisition(TDOCT)andFourier-domainacquisition(FDOCT)(Figure2)