预览加载中，请您耐心等待几秒...

响应面法提取枣皂苷工艺的优化.docx

预览
1/2
2/2

在线预览结束，喜欢就下载吧，查找使用更方便

下载提示 文本预览

如果您无法下载资料，请参考说明：

1、部分资料下载需要金币，请确保您的账户上有足够的金币

2、已购买过的文档，再次下载不重复扣费

3、资料包下载后请先用软件解压，在使用对应软件打开

响应面法提取枣皂苷工艺的优化 Title:OptimizationofZizyphussaponinsExtractionProcessusingResponseSurfaceMethodology Abstract: Zizyphussaponins,alsoknownasZaoZhiGan,areaclassofbioactivecompoundsfoundinZiziphusjujubaMillfruits,whichhavebeentraditionallyusedinChinesemedicinefortheirvarioushealthbenefits.Inthisstudy,theextractionofZizyphussaponinsfromZiziphusjujubafruitswasoptimizedusingtheresponsesurfacemethodology(RSM).RSMisastatisticalapproachusedtooptimizeprocessesbasedontherelationshipbetweentheindependentvariablesandtheresponsevariable.TheobjectiveofthisresearchwastodeterminetheoptimalconditionsfortheextractionofZizyphussaponinstomaximizetheiryield. Introduction: ZizyphusjujubaMill,commonlyknownasjujubeorChinesereddate,isafruit-bearingplantwidelycultivatedinChinaandotherpartsofAsia.IthasbeenusedforcenturiesintraditionalChinesemedicineforitstherapeuticproperties.Amongitsbioactiveconstituents,Zizyphussaponinshaveattractedsignificantattentionduetotheirpotentialhealthbenefits,includingantioxidant,anti-inflammatory,andanticanceractivities.Therefore,optimizingtheextractionprocessofZizyphussaponinsisofgreatimportanceinordertomaximizetheiryieldandenhancetheirpotentialapplications. Methods: TheextractionofZizyphussaponinswascarriedoutusingasolventextractionmethod.Theindependentvariablesconsideredforoptimizationweretheextractiontime,solvent-to-materialratio,andextractiontemperature.Thelevelsofthesevariableswereselectedbasedonpreliminaryexperimentsandliteraturereview.Theresponsevariable,i.e.,theyieldofZizyphussaponins,wasusedtoevaluatetheoptimizationprocess. ResultsandDiscussion: TheextractionprocesswasoptimizedusingtheBox-Behnkendesign,whichgeneratedatotalof15experimentalruns.Theexperimentaldatawerefittedtoasecond-orderpolynomialequation,andthecoefficientofdetermination(R^2)wasusedtoassessthemodel'sfitness.TheR^2valueof0.9683indicatedahighcorrelationbetweenthevariablesandresponse. Theanalysisofvariance(ANOVA)wasusedtoassessthesignificanceofthemodelanddeterminetheoptimalconditionsforZizyphu