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非ST段抬高型急性心肌梗死患者ST段压低与否的冠脉病变特征比较.docx

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非ST段抬高型急性心肌梗死患者ST段压低与否的冠脉病变特征比较 Title:ComparisonofCoronaryArteryDiseaseFeaturesAssociatedwithSTSegmentDepressioninNon-STSegmentElevationAcuteMyocardialInfarctionPatients Introduction: Non-STsegmentelevationacutemyocardialinfarction(NSTEMI)isatypeofheartattackcharacterizedbyischemicmyocardialinjurywithoutsignificantSTsegmentelevationontheelectrocardiogram(ECG).However,STsegmentdepressionmaypresentinsomeNSTEMIpatients,indicatingunderlyingcoronaryarterydisease(CAD).ThisstudyaimstocomparethecoronaryarterydiseasefeaturesassociatedwithSTsegmentdepressioninNSTEMIpatients. Methods: AliteraturereviewwasconductedtoidentifyrelevantstudiesinvestigatingthecorrelationbetweenSTsegmentdepressionandcoronaryarterydiseaseinNSTEMIpatients.Theselectedstudiesincludedthosewithasufficientsamplesize,cleardefinitionsofSTsegmentdepression,andcomprehensiveassessmentofcoronaryarterydiseasefeatures.Dataonpatientdemographics,cardiacriskfactors,angiographicfindings,andclinicaloutcomeswereextractedfromtheincludedstudies. Results: TheresultsoftheliteraturereviewrevealedseveralkeyfindingsregardingthecoronaryarterydiseasefeaturesassociatedwithSTsegmentdepressioninNSTEMIpatients. 1.Degreeandextentofcoronaryarterystenosis:NSTEMIpatientswithSTsegmentdepressiontendtohaveahigherprevalenceandseverityofcoronaryarterystenosiscomparedtothosewithoutSTsegmentdepression.ThepresenceofSTsegmentdepressionisassociatedwithagreaternumberofstenoticvesselsandincreasedoveralldiseaseburden. 2.Multivesseldisease:NSTEMIpatientswithSTsegmentdepressionaremorelikelytopresentwithmultivesseldisease(MVD)comparedtothosewithoutSTsegmentdepression.Theinvolvementofmultiplecoronaryarteriescontributestoahigherriskofadversecardiaceventsandrequiresaggressivemanagementstrategies. 3.Leftmaincoronaryarteryinvolvement:STsegmentdepressioninNSTEMIpatientsoftenindicatesinvolvementoftheleftmaincoronaryartery,whichisacriticalarterysupplyingalargeportionofthemyocardium.Leftmaindiseaseisassociatedwithahigherriskofmajoradversecardiaceventsandmayneces