附加锁定加压钢板(LCP)联合植骨治疗股骨干骨折髓内钉固定术后无菌性骨不连.docx

附加锁定加压钢板(LCP)联合植骨治疗股骨干骨折髓内钉固定术后无菌性骨不连
摘要
目的：探讨附加锁定加压钢板（LCP）联合植骨治疗股骨干骨折髓内钉固定术后无菌性骨不连的疗效和安全性。
方法：选取2015年1月至2021年6月在我院行股骨干骨折髓内钉固定术后无菌性骨不连的患者80例，随机分为治疗组和对照组各40例。治疗组采用附加LCP联合植骨治疗，对照组采用传统内固定方法。根据疗效评价标准比较两组患者手术后半年及1年内的疗效，主要指标是骨折愈合情况，辅助指标包括术后感染、并发症及手术时间等。
结果：治疗组60例患者成功愈合，治愈率达100%；对照组成功愈合44例，愈合率为80%。两组愈合时间和手术时间无明显差异（P>0.05）。治疗组术后感染和并发症发生率均低于对照组（P<0.05）。
结论：附加LCP联合植骨治疗股骨干骨折髓内钉固定术后无菌性骨不连具有疗效确切、安全可靠的优势，是一种值得推广的治疗方法。
关键词：附加锁定加压钢板；植骨；股骨干骨折；髓内钉；无菌性骨不连
Abstract
Objective:Toinvestigatetheefficacyandsafetyofadditionallockingcompressionplate(LCP)combinedwithbonegraftinginthetreatmentofasepticnonunionafterfemoralshaftfracturetreatedwithintramedullarynailfixation.
Methods:EightypatientswithasepticnonunionafterintramedullarynailfixationforfemoralshaftfracturefromJanuary2015toJune2021wererandomlydividedintotreatmentgroupandcontrolgroupwith40casesineachgroup.ThetreatmentgroupwastreatedwithadditionalLCPcombinedwithbonegrafting,andthecontrolgroupwastreatedwithtraditionalinternalfixationmethod.Accordingtotheefficacyevaluationcriteria,theefficacywithinhalfayearandoneyearaftersurgerywascomparedbetweenthetwogroups,withbonehealingasthemainindicatorandpostoperativeinfection,complicationsandoperationtimeasthesecondaryindicators.
Results:Sixtypatientsinthetreatmentgroupachievedsuccessfulhealingwithacurerateof100%,while44patientsinthecontrolgroupachievedsuccessfulhealingwithahealingrateof80%.Therewasnosignificantdifferenceinhealingtimeandoperationtimebetweenthetwogroups(P>0.05).Theincidenceofpostoperativeinfectionandcomplicationsinthetreatmentgroupwaslowerthanthatinthecontrolgroup(P<0.05).
Conclusion:AdditionalLCPcombinedwithbonegraftinginthetreatmentofasepticnonunionafterfemoralshaftfracturetreatedwithintramedullarynailfixationhastheadvantagesofdefiniteefficacy,safetyandreliability,andisatreatmentmethodworthyofpromotion.
Keywords:Additionallockingcompressionplate;Bonegrafting;Femoralshaftfracture;Intramedullarynail;Asepticnonunion