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系统性红斑狼疮中医组方用药规律研究.docx

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系统性红斑狼疮中医组方用药规律研究 Systemiclupuserythematosus(SLE)isachronicautoimmunedisorderthatcanaffectmultipleorgansandsystems,includingtheskin,joints,kidneys,andcentralnervoussystem.TraditionalChinesemedicine(TCM)hasbeenusedforcenturiestotreatSLEandotherautoimmuneconditions,andtheuseofTCMincombinationwithconventionalmedicaltreatmenthasshownpromisingresults. TheTCMpatterndifferentiationandtreatmentofSLEisbasedontheprinciplesofTCM,whichincludetonifyingtheqiandblood,regulatingtheyinandyang,andclearingheatanddampness.SLEischaracterizedbyadeficiencyofqiandblood,whichleadstoyindeficiencyandheataccumulation.ThepathogenesisofSLEinTCMisbelievedtoinvolvetheaccumulationofpathogenicfactorssuchaswind,heat,dampness,andphlegm,whichleadtoanimbalanceofthebody'syinandyangandthedisruptionoftheharmoniousflowofqiandblood. TheTCMtreatmentofSLEistailoredtotheindividual'sspecificpatternofdisharmony.Generally,TCMtreatmentinvolvestheuseofherbalformulas,acupuncture,anddietarytherapy.Theselectionofherbsandacupuncturepointsvariesaccordingtothepatient'spresentingsignsandsymptoms,aswellastheiroverallconstitution. ThereareseveralcommonTCMherbalformulasusedforthetreatmentofSLE,includingWuWeiXiaoDuYin,XiaoChaiHuTang,LiuWeiDiHuangWan,andJinGuiShenQiWan.WuWeiXiaoDuYinisaformulathatisusedtoclearheatandtoxicityfromthebody,whichisbelievedtobeacontributingfactorinSLE.XiaoChaiHuTangisaformulathatisusedtoregulatetheflowoftheliverqi,whichisoftendisruptedincasesofSLE.LiuWeiDiHuangWanisaformulathattonifiestheyinandnourishestheblood,whichisoftendeficientinpatientswithSLE.JinGuiShenQiWanisaformulathattonifiesthekidneyyangandnourishesthekidneyyin,whichcanhelptoimprovethebody'sabilitytoregulateitsownimmuneresponse. Inadditiontoherbalformulas,acupunctureisoftenusedasacomplementarytherapyforSLE.Acupuncturepointsareselectedbasedonthepatient'sspecificpatternofdisharmony,withthegoalofregulatingtheflowofqiandbloodandrestoringbalancetothebody.Acupuncturecanbeparticularlyeffectiveforreducingpain,inflammation,andfatigue,whicharecommo