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苦参总黄酮提取工艺研究进展.docx

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苦参总黄酮提取工艺研究进展 Title:ResearchProgressontheExtractionProcessofTotalFlavonoidsfromSophoraflavescens Abstract: Sophoraflavescens,alsoknownasSophoraeRadix,isatraditionalChinesemedicinalherb.Itcontainsvariousbioactivecompounds,includingflavonoids,alkaloids,andpolysaccharides,thatpossessawiderangeofpharmacologicalactivities.Amongthem,totalflavonoidsareconsideredasthemajoractivecomponentsresponsibleforthetherapeuticeffects.ThispaperaimstoprovideanoverviewoftheresearchprogressontheextractionprocessoftotalflavonoidsfromSophoraflavescens,includingdifferentextractionmethods,optimizationofextractionconditions,andtheireffectsontheyieldandqualityofflavonoids.Italsohighlightsthepotentialapplicationsandfutureperspectivesofutilizingtheseextractedtotalflavonoids. 1.Introduction 2.ConstituentsandPharmacologicalActivitiesofSophoraflavescens 2.1Flavonoids 2.2Alkaloids 2.3Polysaccharides 3.ExtractionMethodsofTotalFlavonoidsfromSophoraflavescens 3.1Traditionalmethods 3.1.1Waterextraction 3.1.2Ethanolextraction 3.1.3Methanolextraction 3.2Modernmethods 3.2.1Supercriticalfluidextraction(SFE) 3.2.2Microwave-assistedextraction(MAE) 3.2.3Ultrasonic-assistedextraction(UAE) 3.2.4Subcriticalwaterextraction(SWE) 4.OptimizationofExtractionConditionsforTotalFlavonoids 4.1Selectionofsolvent 4.2Extractiontime 4.3Extractiontemperature 4.4Solid-liquidratio 5.EffectsofExtractionMethodsandConditionsonYieldandQualityofTotalFlavonoids 5.1Yieldoftotalflavonoids 5.2Contentandcompositionofflavonoids 5.3Biologicalactivitiesofextractedflavonoids 6.ApplicationsofExtractedTotalFlavonoidsfromSophoraflavescens 6.1Anti-inflammatoryactivity 6.2Antioxidantactivity 6.3Anticanceractivity 6.4Antimicrobialactivity 7.FuturePerspectives 7.1Developmentofnovelextractionmethods 7.2Isolationandidentificationofindividualflavonoids 7.3Formulationanddeliverysystemsoftotalflavonoids 8.Conclusion Keywords:Sophoraflavescens,totalflavonoids,extractionmethods,optimization,yield,quality,applications Introduction: Sophoraflavescens,commonly