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支持得分矩阵的生物序列匹配系统的设计与优化 Title:DesignandOptimizationofaBiologicalSequenceMatchingSystemwithSupportScoringMatrix Abstract: WithadvancementsinDNAsequencingtechnologiesandtheexponentialgrowthofbiologicalsequencedata,thereisanincreasingdemandforefficientandaccuratemethodsforsequencematching.Thispaperaimstoproposeadesignandoptimizationapproachforabiologicalsequencematchingsystemutilizingasupportscoringmatrix.Thesystemisdesignedtoenhancetheaccuracyandspeedofsequencematching,thusprovidingvaluableinsightsintovariousbiologicalprocesses. 1.Introduction 1.1Background 1.2Objective 1.3Significance 1.4Outline 2.LiteratureReview 2.1BiologicalSequenceMatching 2.2ExistingMethods 2.3SupportScoringMatrix 2.4LimitationsofExistingApproaches 3.DesignoftheBiologicalSequenceMatchingSystem 3.1SystemArchitecture 3.2InputandOutput 3.3SupportScoringMatrixConstruction 3.4MatchingAlgorithm 4.OptimizationTechniques 4.1ParallelComputing 4.2IndexingandCompressionMethods 4.3MachineLearningApproaches 4.4BigDataProcessing 5.ExperimentalEvaluation 5.1DataPreparationandPreprocessing 5.2PerformanceMetrics 5.3ComparativeAnalysiswithExistingMethods 5.4ResultsandDiscussion 6.SystemEnhancementsandScalability 6.1Real-TimeMatching 6.2Cloud-BasedImplementation 6.3IntegrationwithOtherResources 6.4ScalabilityandEfficiencyAnalysis 7.ApplicationsandFutureDirections 7.1FunctionalAnnotation 7.2DrugDiscovery 7.3ComparativeGenomics 7.4PersonalizedMedicine 8.Conclusion 8.1SummaryofContributions 8.2ImplicationsandRecommendations 8.3FutureResearchDirections 9.References Thispaperaimstoproposethedesignandoptimizationofabiologicalsequencematchingsystembyleveragingtheadvantagesofasupportscoringmatrix.Thesupportscoringmatrixisanenhancedrepresentationofbiologicalsequencesthattakesintoaccounttherelativeimportanceorfrequencyofindividualsequenceelements.Byutilizingthismatrix,thesystemcanachievehigheraccuracyandspeedinsequencematching. Thedesignofthesystemincludesdefiningthesystemarchitecture,input,andoutputformats,aswellasconstructi