预览加载中，请您耐心等待几秒...

二维斑点追踪技术对原发性高血压患者心肌应变的研究.docx

预览
1/6
2/6
3/6
4/6
5/6
6/6

在线预览结束，喜欢就下载吧，查找使用更方便

下载提示 文本预览

如果您无法下载资料，请参考说明：

1、部分资料下载需要金币，请确保您的账户上有足够的金币

2、已购买过的文档，再次下载不重复扣费

3、资料包下载后请先用软件解压，在使用对应软件打开

二维斑点追踪技术对原发性高血压患者心肌应变的研究 Abstract Introduction:Primaryhypertensionisacommoncardiovasculardiseasethatcanleadtovariouscomplications,includingmyocardialdysfunction.Two-dimensionalspeckletracking(2D-ST)isanovelimagingtechniquethatallowsfortheassessmentofmyocardialstrain,whichisasensitiveindicatorofmyocardialfunction. Objective:Thisstudyaimstoinvestigatetherelationshipbetween2Dspeckletrackingmeasurementsandmyocardialstraininpatientswithprimaryhypertension,inordertobetterunderstandtheimpactofhypertensiononmyocardialfunction. Methods:Atotalof100primaryhypertensionpatientsand100healthycontrolswereincludedinthisstudy.Allparticipantsunderwentechocardiographytoassessleftventricularfunction.2Dspeckletrackingwasusedtomeasuregloballongitudinalstrain(GLS),circumferentialstrain(CS),andradialstrain(RS). Results:TheprimaryhypertensiongrouphadsignificantlylowerGLS(-16.2vs.-19.8,p<0.001),CS(-20.4vs.-23.9,p<0.001),andRS(36.8vs.45.7,p<0.001)comparedtothecontrolgroup.Theseresultsindicateimpairedmyocardialstraininpatientswithprimaryhypertension.Furthermore,theseverityofhypertension,asindicatedbybloodpressurelevels,wasnegativelycorrelatedwithGLS(r=-0.567,p<0.001),CS(r=-0.532,p<0.001),andRS(r=-0.445,p<0.001).Thissuggeststhatasbloodpressureincreases,myocardialstraindecreases. Conclusion:Ourfindingsdemonstratethatprimaryhypertensionisassociatedwithimpairedmyocardialstrain,asmeasuredby2Dspeckletracking.Thissuggeststhathypertensionleadstomyocardialdysfunction,whichmaycontributetothedevelopmentofcardiovascularcomplicationsinhypertensivepatients.Furtherresearchisneededtoexploretheprecisemechanismsunderlyingthisrelationshipandtoassesstheclinicalsignificanceofthesefindings. Keywords:Primaryhypertension,myocardialstrain,2Dspeckletracking,echocardiography,leftventricularfunction. Introduction Primaryhypertension,alsoknownasessentialhypertension,isachronicmedicalconditioncharacterizedbypersistentlyelevatedbloodpressurelevels.Itisamajorriskfactorforcardiovasculardiseases,includingcoronaryarterydisease,s