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桥本脑病(Hashimoto’sEncephalopathy,HE)提纲现病史(1)现病史(2)既往史查体辅助检查(1)腰穿诊断、治疗及预后桥本脑病综述概念(1)概念(2)桥本脑病(HE)的流行病学HE临床表现(1)HE临床表现(2)HE临床表现(3)HE的实验室检查-血清学HE的实验室检查-甲状腺功能HE的实验室检查-甲状腺抗体HE的腰穿结果HE的实验室检查-EEG和血管造影HE的影像学Figure2.AxialT2-weightedMRIbrainscanthroughthetemporallobesshowsbilateralareasofincreasedsignalintensityinvolvingthemesialtemporallobesandhippocampi(arrows). Fig.2MRIonedayafteradmission:axialFLAIRimagesshowwidespreadhyperintensesignalsoverthelefttemporalandbothparieto-occipitallobesinthesubcorticalwhitematterHE病理DuffeyP.Hashimoto'sencephalopathy:postmortemfindingsafterfatalstatusepilepticus.Neurology.2003Oct28;61(8):1124-6.Theneuropathologicalfeaturesincludediscreteareasofemyelination(G;areasofpalloronHematoxylinandEosin[arrowheads],H;LuxolFastBluestaining)withrelativereservationofaxons(I;Bielschowskystaining).ThelackoferivascularcuffsisevidentintheHematoxylinandEosinstaining(G).HE的诊断鉴别诊断发病机制关于发病机制的两种学说(1)关于发病机制的两种学说(2)治疗流程治疗预后该病给我们的启示对该病将来研究的展望关于甲状腺疾病和神经系统的关系