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神经元和神经胶质细胞-胶质细胞.pptx

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会计学Abletoreplicate! ImportanceinnervoussystemfunctionisVASTLYunderestimated! Evidenceismounting: Nurturingrole Signalingrole(Memory?) Inflammation Pain Manymoretocome! Presenceoftightjunctionsbetweentheendothelialcells Oneofthenotablefeaturesofendothelialcellsincomparisontoothercellisthelackofpinocyticvesicles Selectivepermeabilitytomoleculesbasedontheirmolecularweightandlipidsolubility Presenceofspecificmarkers Richintwoenzymes:gammaglutamyltranspeptidase(GGTP)(foraminoacidtransport)andalkalinephosphatase(transportofphsopahteions)usedasmarkerforBBB. Others:glucosetransporter(GLUT-1);endothelialbarrierantigen(EBA;unknownfunction)andantigenrecognizedbytheMRCOX-47monoclonalantibody(importantforcell-to-celladhesion);transferrinreceptor(transportofferricions).BBB1.NeuronshaveTWO"processes"calledaxonsanddendrites.GlialcellsonlyhaveONE. 2.NeuronsCANgenerateactionpotentials.GlialcellsCANNOT,however,dohavearestingpotential. 3.NeuronsHAVEsynapsesthatuseneurotransmitters.GlialcellsdoNOThavechemicalsynapses. 4.NeuronsdoNOTcontinuetodivide.GlialcellsDOcontinuetodivide. 5.TherearemanyMORE(10-50timesmore)glialcellsinthebraincomparedtothenumberofneurons.NerveCellsNeurons,Glia,ExtracellularSpace,andBloodBidirectionalCommunicationPartners intheCNSMetabolismofAstrocytesandtheirMetabolicCooperationwithNeuronsThreeTypesofMetabolicCooperationofAstrocytesandNeurons感谢您的观看！