替卡格雷杂质列表-杂质对照品.pdf

替卡格雷杂质列表-杂质对照品

序号杂质名称或编号英文名CAS结构式及CAS

Ticagrelor
1替卡格雷杂质A
ImpurityA

Ticagrelor
2替卡格雷杂质B
ImpurityB

Ticagrelor
3替卡格雷杂质C
ImpurityC

S
(S)F
N
NN(R)
TicagrelorHOO(S)F
(R)N
4替卡格雷杂质DNHN
impurityD(R)
(S)
O
O

S
(S)F
N
TicagrelorNN(R)
5HOO(S)F
替卡格雷杂质E(R)N
impurityENHN
HO(S)(S)
OH

NHN
N(R)(S)
TicagrelorO(R)NN
6替卡格雷杂质FF
impurityFON
O(S)
(S)S
(S)OHF
HO
HO

Ticagrelor
7替卡格雷杂质G
impurityG

Ticagrelor
8替卡格雷杂质H
impurityH

NOH
N
HON
Ticagrelor(R)N
9替卡格雷杂质IN
impurityIO(S)
(S)S
(S)OH
HO

H2NCl
H
HO
Ticagrelor(R)NN
10替卡格雷杂质JN
impurityJO(S)
(S)S
(S)OH
HO
NCl
N
HO
Ticagrelor(R)NN
11替卡格雷杂质KN
impuritykO(S)
(S)S
(S)OH
HO

NHN
N(R)(S)
HO
Ticagrelor(R)NN
12替卡格雷杂质LF
impurityLN
O(S)
(S)S
(S)OHF
HOO

NHN
N(R)(S)
HO
Ticagrelor(R)NN
13替卡格雷杂质MF
impurityMNO
O(S)
(S)S
(S)OHF
HOO
Ticagrelor
14替卡格雷杂质N
impurityN

1、阿考替胺杂质2、维格列汀杂质3、厄洛替尼杂质4、利伐沙班杂质5、索拉非尼杂质
6、阿伐那非杂质7、替卡格雷杂质8、阿哌沙班杂质9、米格列奈杂质10、普拉克索杂
质11、氨氯地平杂质12、非不司他杂质13、托法替尼杂质14、达比加群酯杂质15、埃
相关索美拉唑钠杂质16、盐酸氨溴索杂质17、卡格列净杂质18索菲布韦杂质19、依托考昔
杂质杂质
及代理其他品牌杂质标准品（EP、USP、LGC、TRC、TLC、MC、SINCO）等。
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