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超重及肥胖与脂肪肝关系的病例对照分析_钟朝晖.pdf

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中国组织工程研究与临床康复第11卷第39期2007-09-30出版JournalofClinicalRehabilitativeTissueEngineeringResearchSeptember30,2007Vol.11,No.39CRTER临床医学超重及肥胖与脂肪肝关系的病例对照分析*★钟朝晖1,程朝英2,何艳辉1,廖蓉2,徐小利3Relationshipofoverweightandobesitytofattyliver:Acase-controlstudy1DepartmentofEpidemiology,AbstractChongqingMedicalUniversity,ChongqingAIM:Toanalyzetherelationshipofoverweightandobesitywithfattyliver,andexploretheinteractionofobesityand400016,China;2Theotherriskfactorsintheincidenceoffattyliver.EighthPeople'sMETHODS:Totally2458communityresidentswereenrolledbymeansofstratifiedmultistageclustersamplingbetweenHospitalofChongqing,September2002andDecember2004.Accordingto1:1matchedcase-controlstudy,thisinvestigationadopted425Chongqing400010,casesdiagnosedasfattyliverbyBultrasoundand425controlsmatchedbysex,ageandinhabitancy.TheyagingoverChina;3TheFifthPeople'sHospitalof18yearsallreceivedthepersonalinterviewandphysicalexamination.Chongqing,RESULTS:All850subjectswereinvolvedintheresultanalysis.TherisksoftheincidenceoffattyliverinoverweightChongqing400062,Chinaandobesitygroupweresignificantlyhigherthanthatinnormalbodyweightgroup(OR=4.07,OR95%CI=2.99-5.54).Theoddsratio(OR)increasedwiththebodymassindex,showingthecleardose-responserelationship(TendencyZhongZhao-hui★,2Master,Associateχ=104.25,P<0.0001).Thediseaseriskofabdominalobesitypersonswithabnormalwaisthipratiowashigherprofessor,Departmentthanthosewithoutabdominalobesity.InteractionanalysissuggestedthatobesityplusdrinkinghabitcouldsignificantlyofEpidemiology,increasetheriskoffattyliver.Itsrelativeexcessriskofinteractionwas8.16,anditsattributableproportionofChongqingMedicalUniversity,Chongqinginteractionwas0.5767.400016,ChinaCONCLUSION:Thereisacloserelationshipofoverweightandobesitywiththeincidenceoffattyliver,andasignificantlyzzhlxb@sohu.comsynergisticinteractioneffectbetweenobesityanddrinkinghabitindevelopingfattyliver.ThemeasurementtocontroltheSupportedby:bodyweightisessentialfordecreasingtheprevalencerateoffattyliver.ScientificResearchFoundationofChongqing